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İzahPoliovirus life cycle.png
The cellular life cycle of poliovirus. It is initiated by binding of a poliovirion to the cell surface macromolecule CD155, which functions as the receptor (1). Uncoating of the viral RNA is mediated by receptor-dependent destabilization of the virus capsid (2). Cleavage of the viral protein VPg is performed by a cellular phosphodiesterase, and translation of the viral RNA occurs by a cap-independent (IRES-mediated) mechanism (3). Proteolytic processing of the viral polyprotein yields mature structural and non-structural proteins (4). The positive-sense RNA serves as template for complementary negative-strand synthesis, thereby producing a double-stranded RNA (replicative form, RF) (5). Initiation of many positive strands from a single negative strand produces the partially single-stranded replicative intermediate (RI) (6). The newly synthesized positive-sense RNA molecules can serve as templates for translation (7) or associate with capsid precursors to undergo encapsidation and induce the maturation cleavage of VP0 (8), which ultimately generates progeny virions. Lysis of the infected cell results in release of infectious progeny virions (9).
Tarix
Mənbə
De Jesus NH (2007). "Epidemics to eradication: the modern history of poliomyelitis". Virol. J.4: 70. DOI:10.1186/1743-422X-4-70. PMID 17623069.
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Nidia H De Jesus (image and caption)
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{{Information |Description= The cellular life cycle of poliovirus. It is initiated by binding of a poliovirion to the cell surface macromolecule CD155, which functions as the receptor (1). Uncoating of the viral RNA is mediated by receptor-dependent desta
fayl, poliovirus, life, cycle, fayl, faylın, tarixçəsi, fayl, keçidləri, faylın, qlobal, istifadəsisınaq, göstərişi, ölçüsü, piksel, digər, ölçülər, piksel, piksel, piksel, piksel, faylın, orijinalı, 8206, piksel, fayl, həcmi, mime, növü, image, fayl, vikimedi. Fayl Faylin tarixcesi Fayl kecidleri Faylin qlobal istifadesiSinaq gosterisi olcusu 739 599 piksel Diger olculer 296 240 piksel 592 480 piksel 947 768 piksel 1 202 975 piksel Faylin orijinali 8206 1 202 975 piksel fayl hecmi 276 KB MIME novu image png Bu fayl Vikimedia Commons dadirve diger layihelerde istifade edile biler Faylin tesvir sehifesine get IzahPoliovirus life cycle png The cellular life cycle of poliovirus It is initiated by binding of a poliovirion to the cell surface macromolecule CD155 which functions as the receptor 1 Uncoating of the viral RNA is mediated by receptor dependent destabilization of the virus capsid 2 Cleavage of the viral protein VPg is performed by a cellular phosphodiesterase and translation of the viral RNA occurs by a cap independent IRES mediated mechanism 3 Proteolytic processing of the viral polyprotein yields mature structural and non structural proteins 4 The positive sense RNA serves as template for complementary negative strand synthesis thereby producing a double stranded RNA replicative form RF 5 Initiation of many positive strands from a single negative strand produces the partially single stranded replicative intermediate RI 6 The newly synthesized positive sense RNA molecules can serve as templates for translation 7 or associate with capsid precursors to undergo encapsidation and induce the maturation cleavage of VP0 8 which ultimately generates progeny virions Lysis of the infected cell results in release of infectious progeny virions 9 Tarix 2007 Menbe De Jesus NH 2007 Epidemics to eradication the modern history of poliomyelitis Virol J 4 70 DOI 10 1186 1743 422X 4 70 PMID 17623069 Muellif Nidia H De Jesus image and caption Icaze Faylin tekrar istifadesi This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited Bu fayl Creative Commons Attribution 2 0 Generic lisenziyasi altinda yayimlanir Azadsiniz paylasmaq eseri kocurmek paylamaq ve oturmek ucun remiks etmek eseri adaptasiya etmek Asagidaki sertlere riayet etmekle istinad Muvafiq kredit vermelisiniz lisenziyaya bir kecid vermelisiniz ve deyisikliklerin olub olmadigini bildirmelisiniz Bunu her hansi bir aglabatan sekilde ede bilersiniz ancaq lisenziyalasdiricinin sizi ve ya istifadenizi tesdiqlemesini teklif eden bir sekilde deyil https creativecommons org licenses by 2 0 CC BY 2 0 Creative Commons Attribution 2 0 true trueCaptionsazerbaycancaAdd a one line explanation of what this file representsItems portrayed in this filetesvir edircopyright status nbsp ingiliscopyrighted nbsp ingilislisenziyaCreative Commons Attribution 2 0 Generic nbsp ingilisyaranma tarixi2007 Faylin tarixcesi Faylin evvelki versiyasini gormek ucun gun tarix bolmesindeki tarixlere klikleyin Tarix VaxtKicik sekilOlculerIstifadeciSerh indiki16 29 26 sentyabr 20071 202 975 276 KB DO11 10 Information Description The cellular life cycle of poliovirus It is initiated by binding of a poliovirion to the cell surface macromolecule CD155 which functions as the receptor 1 Uncoating of the viral RNA is mediated by receptor dependent desta Fayl kecidleri Bu sekile olan kecidler Ribonuklein tursusu Faylin qlobal istifadesi Bu fayl asagidaki vikilerde istifade olunur bn wikipedia org layihesinde istifadesi প ল ও ভ ইর স bs wikipedia org layihesinde istifadesi Poliovirus cs wikipedia org layihesinde istifadesi Wikipedista Yennefer1 Poliovirus Poliovirus da wikipedia org layihesinde istifadesi Poliovirus en wikipedia org layihesinde istifadesi Poliovirus User ChemStudent24601 sandbox gl wikipedia org layihesinde istifadesi Poliovirus hy wikipedia org layihesinde istifadesi ՌՆԹ Պոլիովիրուս ja wikipedia org layihesinde istifadesi ポリオウイルス ru wikipedia org layihesinde istifadesi Ribonukleinovaya kislota Poliovirus si wikipedia org layihesinde istifadesi ම ද හත කරණය sw wikipedia org layihesinde istifadesi Virusi vya Polio ta wikipedia org layihesinde istifadesi ப ல ய வ ரஸ tr wikipedia org layihesinde istifadesi Poliovirus Menbe https az wikipedia org wiki Fayl Poliovirus life cycle png, wikipedia, oxu, kitab, kitabxana, axtar, tap, hersey,
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